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The Journal of Thoracic and Cardiovascular Surgery, Vol 101, 917-923, Copyright © 1991 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
RC Franklin, DJ Spiegelhalter, RH Anderson, FJ Macartney, RI Rossi Filho, ML Rigby and JE Deanfield
The influence of palliation on survival was studied in 191 consecutive
infants, presenting at under 1 year of age, with double-inlet ventricle
(1973 to 1988, median follow-up 8.5 years). Palliative operations were
performed on 154 occasions in 121 patients (63%). Survival after a
systemic-pulmonary arterial shunt (n = 57) and banding of the pulmonary
trunk (n = 35) was comparable (84% and 77% at 1 year, 62% and 45% at 5
years), but those who underwent repair of aortic arch obstruction fared
worse (n = 18, 44% and 22% at 1 and 5 years, p less than 0.001). The
remainder did not undergo an operation because of balanced physiology (n =
17, 9% of entire group), complex anatomy (n = 32, 15%), or irreversible low
output (n = 19, 12%). Palliative surgery, overall, had a deleterious effect
on immediate survival (greater than 1 month relative risk 6.6, p less than
0.001), but, in the survivors, medium- term outcome was improved (greater
than 6 months, 0.68, p less than 0.05). This effect was most marked for
those undergoing a systemic- pulmonary artery shunt (less than 1 month,
2.52; greater than 6 months, 0.43); by contrast, after banding of the
pulmonary trunk, with or without additional repair of the aortic arch
repair, medium-term risk was not altered (greater than 6 months, 1.13 and
0.91, respectively). These data will assist the clinician in making
decisions concerning the management of infants with double-inlet ventricle
and in the judicious use of palliative surgery.
ARTICLES
Double-inlet ventricle presenting in infancy. II. Results of palliative operations
Thoracic Unit, Hospital For Sick Children, London, England.
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