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The Journal of Thoracic and Cardiovascular Surgery, Vol 104, 487-490, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
K al Jubair, MR al Fagih, A Ashmeg, M Belhaj and W Sawyer
Between December 1982 and March 1990, 65 patients with active infective
endocarditis underwent cardiac operations. Their mean age was 28.6 years
(range 1 to 65 years). The most common infecting organisms were
staphylococcus (33.8%), streptococcus (18.5%), and brucella (16.9%); 11
patients (16.9%) had cultures negative for infection. A rheumatic, native
valve, most commonly the aortic, was involved in 40 patients, a prosthetic
valve (with the mitral most common) in 18 patients, and in seven patients
the infection involved a congenitally abnormal valve. Aortic root abscess
developed in 21.5% of patients. In 30 patients operation was performed
within 3 days of the start of intravenous antibiotic therapy, usually
within 3 days of admission (group A); this resulted in fewer preoperative
complications and a significantly lower postoperative complication rate
than in those 35 patients who underwent operations more than 3 days after
starting antibiotic therapy (group B). Preoperative embolic phenomena
occurred in eight (12.3%) of the 31 patients who had large, mobile
vegetations (2/16 [12.5%] in group A and 6/15 [40%] in group B). Overall
there was no reinfection. No postoperative paravalvular leaks developed in
group A. Nine patients died in the hospital (13.8%) (four in group A and
five in group B); in all patients the infecting organism was staphylococcal
or fungal. There was one late death. Early operation should always be
considered in active infective endocarditis, especially when a prosthetic
valve is involved or the infecting organism is staphylococcal or fungal.
The disclosure of moderate to large vegetations by two-dimensional
echocardiography is an indication for operation.
ARTICLES
Cardiac operations during active endocarditis
Riyadh Cardiac Centre, Armed Forces Hospital, Saudi Arabia.
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