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The Journal of Thoracic and Cardiovascular Surgery, Vol 104, 1116-1124, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
DJ O'Brien, RM Bauer, H Yarandi, DG Knauf, P Bramblett and JA Alexander
The memories of 20 patients undergoing elective operations on the heart
were assessed by a comprehensive battery of standardized psychometric
tests. Testing was conducted 1 to 2 days before, 7 to 10 days after, and 1
month after each operation. Twenty age-matched, healthy control subjects
were given the same battery of tests at comparable times. Compared with
healthy subjects, the patient group had significantly lower scores on 3 of
19 tests before, 10 of 19 tests 1 week after, and 5 of 19 tests 1 month
after surgical intervention. The patient group had similar test
performances before and 1 week after the operations and improved on 3 of 19
measures 1 month after the operations. Degrees of illness and
cardiopulmonary bypass variables were significantly related to only a small
subset of memory measures. Results of this study are consistent with
previous reports that underscore the contribution of nonspecific aspects of
surgical intervention to neuropsychologic dysfunction in the immediate
postoperative period. We conclude that neither the illness nor the surgical
variables are directly related to substantial variance in cognitive
function after operations on the heart.
ARTICLES
Patient memory before and after cardiac operations
Division of Thoracic and Cardiovascular Surgery, University of Florida, Gainesville.
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