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The Journal of Thoracic and Cardiovascular Surgery, Vol 104, 932-937, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
G Mellgren, LG Friberg and S Bjorkerud
Neonatal operations have improved the prognosis for newborn children with
aortic coarctation. The 30-day mortality of 123 neonates with isolated
coarctation of the aorta collected from nine series was found to be 0.8%.
The subclavian flap angioplasty was the most frequently used surgical
procedure in this collected series. This technique is relatively new,
however, and many questions have yet to be answered. In this study we have
done subclavian flap repair in newborn pigs and followed them up to adult
ages. The pigs were killed 28 or 44 weeks postoperatively, and the aortas
were reexamined. All flaps had grown symmetrically in width and length and
parallel to the growth of the descending thoracic aorta. The flaps were
macroscopically intact. Signs of degenerative processes were not found. The
wall thickness of the subclavian flap increased by growth of the individual
fibroelastic lamellar units in the tunica media. This adaptation to the
increased wall stress occurred early in life. The wall strength of the flap
also increased by thickening of the intimal layer. We conclude that the
subclavian flap is well suited to function as a part of the aorta in adult
life.
ARTICLES
Can we predict the long-term function of the subclavian flap angioplasty?
Department of Pediatric Surgery, East Hospital, Goteborg, Sweden.
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