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The Journal of Thoracic and Cardiovascular Surgery, Vol 104, 1625-1627, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Renal function in patients undergoing cardiopulmonary bypass operations

V Mazzarella, MT Gallucci, C Tozzo, M Elli, R Chiavarelli, B Marino and C Casciani
Istituto di Tipizzaazione Tissutale e problemi della dialisi-CNR di L'Aquila, Rome, Italy.

We evaluate short- and long-term effects on renal functional reserve of cardiopulmonary bypass in 11 patients. A selected group (persistence of renal functional reserve before operation) of 11 adult patients undergoing cardiopulmonary bypass for aorta-coronary bypass were studied. Renal functional reserve tests were performed in all patients before the operation, at postoperative day 9, and at 6 months after operation. Basal glomerular filtration rate did not show significant changes at 9 days and at 6 months after operation. On the contrary, renal functional reserve was absent at 9 days, but it was restored to preoperative levels at 6 months after operation. In conclusion, our data indicate that cardiopulmonary bypass probably causes renal damage that is not sufficient to influence routine renal function parameters.

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