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J Thorac Cardiovasc Surg 1997;113:736-741
© 1997 Mosby, Inc.

SURGERY FOR CONGENITAL HEART DISEASE

AORTIC VALVE REPLACEMENT AFTER REPAIR OF PULMONARY ATRESIA AND VENTRICULAR SEPTAL DEFECT OR TETRALOGY OF FALLOT

Received for publication July 16, 1996 revisions requested Sept. 3, 1996; revisions received Oct. 1, 1996; accepted for publication Oct. 22, 1996. Address for reprints: Carole A. Warnes, MD, Mayo Clinic, W-16, 200 First St. SW, Rochester, MN 55905.

Abstract

Objective: Little attention has been paid to the occurrence of aortic regurgitation after complete repair in patients with pulmonary atresia and ventricular septal defect or tetralogy of Fallot. To highlight the development of aortic regurgitation or aortic root dilation severe enough to necessitate aortic valve replacement with or without aortic aneurysmorrhaphy or aortic root replacement, we retrospectively reviewed the records of patients who underwent aortic valve operation at our institution subsequent to repair of pulmonary atresia and ventricular septal defect or tetralogy of Fallot.

Methods: We searched the Mayo Clinic database for patients with pulmonary atresia and ventricular septal defect or tetralogy of Fallot who subsequently had aortic valve or aortic root operations. The degree of aortic regurgitation before operation was noted. Aortic sinus and root dimensions were measured.

Results: Sixteen patients underwent complete repair at a median age of 17 years, followed by an aortic operation a median of 13.5 years later. All 16 patients had dilated aortic sinuses at the time of the aortic valve operation. These 16 patients had aortic valve replacement: 11 with mechanical prostheses and 5 with bioprostheses. Five of the 16 also had reduction of aortic dilation by lateral aneurysmorrhaphy, and 1 had graft replacement of the ascending aorta. Five patients had associated conditions (evidence of valvular damage, recurrent ventricular septal defect, or history of endocarditis) discovered at the aortic valve operation that have been reported to be related to the development of aortic regurgitation. The remaining 11 patients had progressive aortic regurgitation despite complete, uncomplicated repair.

Conclusions: Progressive aortic regurgitation and aortic root dilation can occur despite complete repair of pulmonary atresia and ventricular septal defect or tetralogy of Fallot.

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