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J Thorac Cardiovasc Surg 2006;131:779-784
© 2006 The American Association for Thoracic Surgery

Surgery for Congenital Heart Disease

Selective management of the left ventricular outflow tract for repair of interrupted aortic arch with ventricular septal defect: Management of left ventricular outflow tract obstruction

Section of Cardiac Surgery, Division of Pediatric Cardiac Surgery, University of Michigan School of Medicine, Ann Arbor, Mich

Received for publication August 8, 2005; revisions received November 16, 2005; accepted for publication November 21, 2005.

^_* Address for reprints: Richard G. Ohye, MD, F7830 C.S. Mott Children's Hospital, 1500 East Medical Center Dr, Ann Arbor, MI 48109-0223 (Email: ohye{at}umich.edu).

OBJECTIVE: Left ventricular outflow tract obstruction remains an early and late complication after repair of interrupted aortic arch and ventricular septal defect. We reviewed our experience with the selective management of the infundibular septum during primary repair to address left ventricular outflow tract obstruction.

METHODS: From 1991 through 2001, all 27 patients presenting with interrupted aortic arch/ventricular septal defect and posterior deviation of the infundibular septum were analyzed. Fifteen patients with the smallest subaortic areas underwent myectomy or myotomy of the infundibular septum concomitant with interrupted aortic arch/ventricular septal defect repair.

RESULTS: Patients undergoing myectomy-myotomy (Group I) had significantly smaller subaortic diameter indexes (0.83 ± 0.16 cm/m²) when compared with those who had only interrupted aortic arch/ventricular septal defect repair (group 2: 0.99 ± 0.13 cm/m², P = .012). Two hospital deaths occurred in group 1, and 1 occurred in group 2. No late deaths occurred. No patient in group 2 required reoperation. Six group 1 patients required 9 reoperations for left ventricular outflow tract obstruction. Five patients underwent resection of a new subaortic membrane. Only 1 patient had recurrent muscular left ventricular outflow tract obstruction. Three patients required a second reoperation, primarily related to aortic valve stenosis.

CONCLUSIONS: Interrupted aortic arch/ventricular septal defect with posterior malalignment of the infundibular septum can be repaired with low mortality in the neonatal period. Tailored to the degree of subaortic narrowing, resection or incision of the infundibular septum at the time of primary repair was very effective in preventing or prolonging the interval to recurrent left ventricular outflow tract obstruction compared with the published data. However, reoperation for left ventricular outflow tract obstruction, often related to the development of a new and discrete subaortic membrane or valvar stenosis, is still required in a subset of patients.