The Journal of Thoracic and Cardiovascular Surgery, Vol 70, 147-151, Copyright © 1975 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Oat cell carcinoma as a malignant apudoma
LH Smith
The neural crest origin of cells secreting amine and polypeptide hormones
(APUD cells) is a unifying concept. The relationship of the classical
endocrine system to that of tumor hormone secretion can be explained by the
diffuse migration and later neoplasia of these unique cells. This paper
describes the APUD cell origins of oat cell carcinoma.