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The Journal of Thoracic and Cardiovascular Surgery, Vol 70, 229-236, Copyright © 1975 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Reversal of pulmonary circulation

TJ Dosis, F Thevoz, DL Fisher, MH Adatepe, P Merkow and GJ Magovern

The preliminary results and the technique of total reversal of the pulmonary circulation (RPC) are presented. Total RPC is technically feasible and not incompatible with life. It affords a new experimental model for in vivo study of pulmonary pathophysiology. The influence of this reversal on blood oxygenation, on pulmonary vascular resistance, and on established pulmonary hypertension, as well as its reaction to hypoxia and acidosis, needs further investigation. RPC may have clinical implications in essential pulmonary hypertension and congenital pulmonary vascular anomalies.


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 Eur. J. Cardiothorac. Surg.Home page
T. Dosios
In vivo model for reversal of pulmonary blood flow in canines
Eur. J. Cardiothorac. Surg., January 1, 2000; 17(1): 88 - 88.
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