The Journal of Thoracic and Cardiovascular Surgery, Vol 70, 790-805, Copyright © 1975 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Pulmonary hyperinflation. A form of barotrauma during mechanical ventilation
OR Baeza, RB Wagner and BD Lowery
Barotrauma has been used to describe several specific complications related
to mechanical ventilation. These include tension lung cyst, pneumothorax,
pneumomediastinum, pneumoperitoneum, and subcutaneous emphysema. Pulmonary
hyperinflation, another such complication, occurred in 6 patients, being
fatal in 3. Two pathophysiologic mechanisms are discussed. The simpler, and
well-recognized, ball-valve airway obstruction allows inspiration of air
delivered by the mechanical ventilator but prevents expiration. A more
complex circumstance exists when pulmonary contusion or infiltration
produces differential lung compliances. This allows extreme hyperinflation
of areas of normal lung during attempts to ventilate abnormal lung of low
compliance. This mechanism is particularly evident when positive end-
expiratory pressure (PEEP) is used in an attempt to open collapsed
ventilatory units. Functional complications of lung hyperinflation include
decreased alveolar ventilation and compression effects on adjacent
structures. Interference with and shifts of regional lung perfusion may
worsen gas exchange. Proper treatment includes airway clearance by
bronchoscopy, the judicious use of bronchodilators, the discontinuance of
PEEP, and adjustments of mechanical ventilators to prevent high airway
pressures.