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The Journal of Thoracic and Cardiovascular Surgery, Vol 71, 614-616, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

The centineurogenic etiology of the respiratory distress syndrome. Protection afforded by anemia and pulmonary denervation against lung lesions of oxygen toxicity

G Moss, P Dworkin and AA Stein

For beagles respiring 100 per cent oxygen at ambient pressure, anemia protected against the development of the lung lesions of oxygen toxicity. Similarly, unilateral pulmonary denervation was protective of the affected lung but not of the normally innervated, contralateral lung. This indicates that the lung lesions are triggered by the toxic effect of elevated PO2 at a remote site, most likely the sensitive central nervous system.




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ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
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Copyright © 1976 by The American Association for Thoracic Surgery.