The Journal of Thoracic and Cardiovascular Surgery, Vol 71, 666-672, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Extracorporeal oxygenation with various experimental venoarterial bypasses during prolonged apnea
CM Derks and P Vanderhoeft
This work compares various conventional venoarterial closed-chest circuits
where satisfactory oxygenation of myocardium and brain in total apnea with
extracorporeal circulation is concerned. Eleven dogs were studied during 3
hours of curare-induced apnea. We used single and double vena caval
drainages connected to an oxygenator. A single-vein drainage yielded
approximately 50 per cent and a double-vein drainage 75 per cent bypass.
Two separate roller pumps fed arterialized blood variously into carotid
and femoral arteries. In single-vein drainage, the oxygen partial pressure
in the coronary artery was consistently poor and carotid oxygen partial
pressure was poor for 100 per cent femoral infusion while more and more
arterialized blood reached the carotid arteries in the other single-vein
drainage circuits. In double- vein drainage, the coronary oxygen partial
pressure for 100 per cent femoral infusion remained poor while, for the
other circuit types, the coronary arteries received arterialized blood
except where 100 per cent carotid infusion was concerned. The carotid
oxygen partial pressure was sound for all groups in the double-vein
drainage except for some obtained in 100 per cent femoral infusion.
Consequently, where the bypass was large and the carotid and femoral
arteries received a share of arterialized blood, both heart and brain
received sound oxygenation.
