The Journal of Thoracic and Cardiovascular Surgery, Vol 71, 750-758, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Operative indication for corrective surgery in cases of complete transposition of the great arteries associated with large ventricular septal defect
A Mori, K Yamaguchi and H Oku
Among 23 patients with complete transposition of the great arteries (TGA)
and large ventricular septal defect (VSD) who underwent corrective surgery,
there were nine deaths (39 per cent). Since 1972, improvement in operative
techniques, linked with increasing experience in postoperative care, has
reduced the hospital mortality rate to 29 per cent (five deaths in 17
patients). Only one of these 23 patients had pulmonary artery banding prior
to definitive repair. Analysis of the preoperative hemodynamic data
suggests that complete surgical repair is not indicated for patients who
have TGA and large VSD, without significant pulmonary stensosis, when the
pulmonary arteriolar resistance is greater than 2,500 dynes-sec.-cm.-5 or
the effective pulmonary flow index is less than 1.2 L. per minute per
square meter of body surface area.