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The Journal of Thoracic and Cardiovascular Surgery, Vol 72, 94-96, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Sarcoma associated with dacron prosthetic material: case report and review of the literature

TX O'Connell, HJ Fee and A Golding

A case of a fibrosarcoma arising in association with a Dacron prosthetic graft is reported. This is the second report of such an association. Animal studies have shown that polymeric substances can induce similar sarcomas and that pore size between the polymeric strands is an important consideration in determining carcinogenicity. Grafts with pore size less than 0.4 mu in diameter should be avoided in man until they are absolutely proved incapable of tumorogenesis.

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