HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Messmer, B. J. Articles by Senning, A. Search for Related Content PubMed PubMed Citation Articles by Messmer, B. J. Articles by Senning, A.

The Journal of Thoracic and Cardiovascular Surgery, Vol 72, 495-502, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Psychomotor and intellectual development after deep hypothermia and circulatory arrest in early infancy

BJ Messmer, U Schallberger, R Gattiker and A Senning

Somatic, psychomotor, and intellectual development were studied in 11 patients who had total correction of congenital cardiac malformation in early infancy by the method of surface-induced deep hypothermia and circulatory arrest up to 43 minutes. Time between operation and re- evaluation ranged from 3 to 11 years (average 7 years). Somatic development was normal in all children. Psychomotor and intellectual behavior, measured by a battery of specially adapted test methods, failed to show a statistically significant difference when compared between the study group, a matched control group, and the normal population. Normal scores in psychomotor tests and normal intelligence quotients (I.Q.) were present in 8 patients; mental retardation was found in 2 patients: and unstable behavior, evident from different tests, was present in one. Except for the last case, in none of the patients was the method was found to be the primary cause of the abnormal behavior. Deep hypothermia and circulatory arrest in early infancy does not appear to have a negative influence on somatic, psychomotor, or intellectual development.

This article has been cited by other articles:

				A. M Karaskov, C S. Kitchlu, and V. N Lomivorotov Cardiac Surgery Under Perfusionless Hypothermia: Siberian Experience Asian Cardiovasc Thorac Ann, March 1, 2002; 10(1): 3 - 7. [Abstract] [Full Text] [PDF]

				H. H. Hovels-Gurich, M.-C. Seghaye, M. Sigler, F. Kotlarek, A. Bartl, J. Neuser, R. Minkenberg, B. J. Messmer, and G. von Bernuth Neurodevelopmental outcome related to cerebral risk factors in children after neonatal arterial switch operation Ann. Thorac. Surg., March 1, 2001; 71(3): 881 - 888. [Abstract] [Full Text] [PDF]

				C. Limperopoulos, A. Majnemer, M. I. Shevell, B. Rosenblatt, C. Rohlicek, and C. Tchervenkov Neurologic Status of Newborns With Congenital Heart Defects Before Open Heart Surgery Pediatrics, February 1, 1999; 103(2): 402 - 408. [Abstract] [Full Text]

				J. H. Kern, V. J. Hinton, N. E. Nereo, C. J. Hayes, and W. M. Gersony Early Developmental Outcome After the Norwood Procedure for Hypoplastic Left Heart Syndrome Pediatrics, November 1, 1998; 102(5): 1148 - 1152. [Abstract] [Full Text]

				S. R. Bernstein, R. Heimler, and P. Sasidharan Normal 17-Month Outcome of a Severely Hypothermic Term Neonate Clinical Pediatrics, March 1, 1998; 37(3): 191 - 195. [PDF]

				B. H. Walpoth, B. N. Walpoth-Aslan, H. P. Mattle, B. P. Radanov, G. Schroth, L. Schaeffler, A. P. Fischer, L. von Segesser, and U. Althaus Outcome of Survivors of Accidental Deep Hypothermia and Circulatory Arrest Treated with Extracorporeal Blood Warming N. Engl. J. Med., November 20, 1997; 337(21): 1500 - 1505. [Abstract] [Full Text] [PDF]

				H. H. Hovels-Gurich, M.-C. Seghaye, S. Dabritz, B. J. Messmer, and G. von Bernuth COGNITIVE AND MOTOR DEVELOPMENT IN PRESCHOOL AND SCHOOL-AGED CHILDREN AFTER NEONATAL ARTERIAL SWITCH OPERATION J. Thorac. Cardiovasc. Surg., October 1, 1997; 114(4): 578 - 585. [Abstract] [Full Text]

				R. K. Oates, J. M. Simpson, J. A. B. Turnbull, and T. B. Cartmill The relationship between intelligence and duration of circulatory arrest with deep hypothermia J. Thorac. Cardiovasc. Surg., September 1, 1995; 110(3): 786 - 792. [Abstract] [Full Text]

				D. C. Bellinger, R. A. Jonas, L. A. Rappaport, D. Wypij, G. Wernovsky, K. C.K. Kuban, P. D. Barnes, G. L. Holmes, P. R. Hickey, R. D. Strand, et al. Developmental and Neurologic Status of Children after Heart Surgery with Hypothermic Circulatory Arrest or Low-Flow Cardiopulmonary Bypass N. Engl. J. Med., March 2, 1995; 332(9): 549 - 555. [Abstract] [Full Text] [PDF]