The Journal of Thoracic and Cardiovascular Surgery, Vol 72, 788-791, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Cardiac manifestations of ochronosis
L Gould, CV Reddy, D DePalma, A De Martino and PE Kalish
A 68-year-old woman with ochronosis was admitted with congestive heart
failure. A typical ejection murmur of aortic stenosis was ausculated and
was documented on a phonocardiogram. The patient subsequently died, and at
autopsy extensive deposition of ochronotic pigment was found on the aortic
valve. This valve had no other anatomic abnormalities. Thus ochronosis
should be considered in the differential diagnosis of aortic stenosis.