The Journal of Thoracic and Cardiovascular Surgery, Vol 72, 801-808, Copyright © 1976 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Pulmonary blastoma
WH Kern and QR Stiles
Two cases of pulmonary blastoma are reported. One occurred in a 29-year-
old man 31 months after a cyst had been excised from the same
pericardial-pleural area. The cyst appeared to be of mesothelial origin
and, although supported by a cellular stroma, was originally considered to
be benign. The morphologic features, location, and possible relationship to
a mesothelial lesion suggest an embryonal-mesothelial origin of the tumor.
The patient died of recurrent and metastatic disease 9 years after the
first resection. The second case is that of a now 74-year-old woman who,
over a period of 19 years, has had six separate small peripheral lung
tumors excised. They originally resembled fibrous hamartomas but included
embryonal-type immature areas and became increasingly more cellular and
sarcomatous. The fine structure of the recurrent tumors is that of
primitive stroma with few fibrils but no other differentiating features.
