HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Yokota, H. Articles by Manabe, H. Search for Related Content PubMed PubMed Citation Articles by Yokota, H. Articles by Manabe, H.

The Journal of Thoracic and Cardiovascular Surgery, Vol 73, 543-549, Copyright © 1977 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Carbohydrate and lipid metabolism in open-heart surgery

H Yokota, Y Kawashima, T Takao, S Hashimoto and H Manabe

Carbohydrate and lipid metabolism was studied in 8 patients who underwent open-heart surgery with the aid of extracorporeal circulation. Hyperglycemia was observed during perfusion. Despite the high glucose levels during perfusion, insulin responses were depressed. A rise of insulin levels was observed one hour after perfusion, and at the same time the glucose levels dropped. Suppression of insulin secretion during perfusion may be the result of increased catecholamine secretion, induced hypothermia, or heparin administration. High levels of non-esterified fatty acids (NEFA) and low levels of triglycerides were observed immediately before, during, and after perfusion while heparin was being utilized. This phenomenon was considered to be strongly affected by the use of heparin. The levels of growth hormone were depressed during perfusion but significantly elevated one hour after the end of perfusion. These phenomena may be caused by the fluctuations in glucose and NEFA levels.

This article has been cited by other articles:

				O. P. Elvenes, C. Korvald, L. M. Ytrebo, O. Irtun, T. Myrmel, T. S. Larsen, and D. Sorlie Myocardial metabolism and efficiency after warm continuous blood cardioplegia Ann. Thorac. Surg., June 1, 2000; 69(6): 1799 - 1805. [Abstract] [Full Text] [PDF]

				H. Braden, S. Cheema-Dhadli, C. D. Mazer, D. J. McKnight, W. Singer, and M. L. Halperin Hyperglycemia During Normothermic Cardiopulmonary Bypass: The Role of the Kidney Ann. Thorac. Surg., June 1, 1998; 65(6): 1588 - 1593. [Abstract] [Full Text] [PDF]