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The Journal of Thoracic and Cardiovascular Surgery, Vol 74, 860-863, Copyright © 1977 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
BR Wilcox, GF Murray and PJ Starek
This study follows the clinical course of 22 patients in the active phase
of infective endocarditis who inderwent valve replacement at North Carolina
Memorial Hospital between March, 1966, and March, 1976. At the time of
operation, there was gross valve tissue destruction in 16 patients,
verrucae in nine, ruptured chordae tendineae in five, and myocardial or
annular abscess formation in five. Four patients survived less than 6
months after the initial operation. One survived almost 3 years before
dying of recurrent carcinoma of the lung. The remaining 17 patients have
been followed an average of 4.6 years. Major postoperative complications
were as follows: paravalvular problem, five patients; congestive heart
failure, seven patients; complete heart block, three patients; systemic
arterial emboli, four patients. These complications often were associated
with the preoperative presence of annular or myocardial abscess. Thus it
appears that postoperative complications often result from annular
structural deficiencies rather than being directly related to active
infection.
ARTICLES
The long-term outlook for valve replacement in active endocarditis
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