The Journal of Thoracic and Cardiovascular Surgery, Vol 75, 519-524, Copyright © 1978 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Role of pulmonary vascular resistance measurements in preoperative evaluation of candidates for pulmonary resection
HJ Fee, EC Holmes, HS Gewirtz, KP Ramming and JM Alexander
Pulmonary function tests (PFT), arterial blood gases (ABG), lung scanning,
and pulmonary artery balloon occlusion with measurement of pulmonary
vascular resistance (PVR) have all been used for preoperative evaluation of
pulmonary function. These tests, however, do not always accurately predict
tolerance to lung resection. We have evaluated a new technique which
promises to increase the accuracy of preoperative evaluation of pulmonary
function. Utilizing a balloon flotation catheter, we measured PVR at
varying cardiac outputs. Forty-five patients underwent this study without
morbidity or mortality. Five of 30 patients who subsequently underwent
pulmonary surgery died of respiratory failure. All of these deaths were
from the high-risk group as determined by PVR. Only one of the five had
been judged to be at high risk by PFT and ABG. This technique has the
advantages of low morbidity and simplicity and should be especially helpful
in the evaluation of those patients who have borderline pulmonary function
as determined by the more standard tests.