The Journal of Thoracic and Cardiovascular Surgery, Vol 75, 569-573, Copyright © 1978 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Comparative studies of pulsatile and nonpulsatile flow during cardiopulmonary bypass. I. Pulsatile system employed and its hematologic effects
KM Taylor, WH Bain, KJ Maxted, MM Hutton, WY McNab and PK Caves
A new, commercially available roller pump system able to deliver pulsatile
and nonpulsatile flow has been studied in patients undergoing elective
open-heart surgical procedures. The pulsatile pump (Stockert Instrumente)
may be used with standard extracorporeal circuit equipment and consistently
produces a peripheral arterial pulse pressure of 25 to 30 mm. Hg at mean
flow rates of 3.5 to 4.0 L. per minute. Twenty patients, arbitrarily
allocated to pulsatile or nonpulsatile groups, have been studied. There
were no significant differences between the groups in respect of age,
weight, bypass time, pump flow, or mean arterial pressure during bypass.
Comparative studies of the hematologic effects of pulsatile and
nonpulsatile perfusion were carried out. There was no evidence of increased
hemolysis with pulsatile flow, nor was there increased depletion of red
blood cells (RBC's) or platelets in the pulsatile group. This pulsatile
pump system may therefore be used to produce pulsatile perfusion during
cardiopulmonary bypass without the fear of producing excessive blood cell
trauma.