The Journal of Thoracic and Cardiovascular Surgery, Vol 77, 466-468, Copyright © 1979 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Deep hypothermic arrest: observations on later development in children
JS Wright, RG Hicks and DC Newman
Thirty-two children were reviewed following closure of ventricular septal
defect in infancy. Fifteen had undergone continuous perfusion and 17 had
been subjected to core cooling followed by deep hypothermic arrest.
Parental and professional evaluations of intellectual and motor
development, at periods between 7 and 72 months following operation,
suggest that there is a higher incidence of developmental abnormality in
the subgroup treated with deep hypothermic arrest.