The Journal of Thoracic and Cardiovascular Surgery, Vol 77, 586-594, Copyright © 1979 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Postcardiotomy delirium: a critical review
WR Dubin, HL Field and DR Gastfriend
The literature concerning postcardiotomy delirium contains confusing
definitions and contradictory results. In a critical review of the subject,
we conclude that cardiac status, the severity of physical illness, the
complexity of the surgical procedure, and preoperative organic brain
disease are the determining factors in postcardiotomy delirium.
Preoperative anxiety, denial, and depression also have some correlation.
Age, sex, time on bypass, and preoperative psychological profile seem to
have no influence on outcome. No psychological etiology for delirium has
been proven consistently. The therapeutic influence of preoperative
interviews in preventing postoperative psychiatric complications remains
equivocal as do theories implicating sensory deprivation in the intensive
care unit. Long-term follow-up studies suggest that psychological problems
impair functional recovery from heart surgery. The suggested treatment of
patients with delirium includes chemotherapy, psychotherapy, and
environmental support. Finally we suggest that investigation of biochemical
abnormalities in delirium may prove to be a model for clarifying the role
of neurotransmitters in functional psychiatric illnesses.