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The Journal of Thoracic and Cardiovascular Surgery, Vol 80, 94-101, Copyright © 1980 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Gore-Tex (polytetrafluoroethylene) in canine coronary artery bypass

JB Hancock, PL Forshaw and MP Kaye

Because of the occasional need for a prosthesis in coronary artery operations, we investigated the potential use of microporous polytetrofluoroethylene (PTFE) with and without antiplatelet drugs as an aorta-coronary bypass graft in 43 dogs. In 13 animals without antiplatelet drugs, no grafts were patent at 1 month. When antiplatelet drugs were used (25 dogs), the 1 month patency rate increased to 64%. The addition of antibiotic treatment 1 month patency rate to 80%. The 6 month patency rate in dogs treated with antiplatelet drugs, preoperative bowel preparation, and systemic antibiotics was 60%. Our data indicate that microporous PTFE grafts used as coronary artery bypass grafts in dogs can be maintained patent for at least 6 months when the animals are treated with antiplatelet drugs.

This article has been cited by other articles:

				A. J. McLarty, M. R. Phillips, D. R. Holmes Jr, and H. V. Schaff Aortocoronary Bypass Grafting With Expanded Polytetrafluoroethylene: 12-Year Patency Ann. Thorac. Surg., May 1, 1998; 65(5): 1442 - 1444. [Abstract] [Full Text] [PDF]

				B. P. Bidstrup Coronary Artery Bypass Graft Patency Seminars in Cardiothoracic and Vascular Anesthesia, November 1, 1997; 1(4): 282 - 287. [Abstract] [PDF]

				R. Fasol, P. Zilla, P. Preiss, U. von Oppell, J. Odell, and B. Reichart Allogenic, Multidonor In Vitro Endothelialization of Small Diameter PTFE Grafts in Baboons Vascular and Endovascular Surgery, January 1, 1991; 25(1): 64 - 71. [Abstract] [PDF]