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The Journal of Thoracic and Cardiovascular Surgery, Vol 81, 546-552, Copyright © 1981 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Intrafamilial lung xenografts from fox to dog

FJ Veith, KU Richards, JW Hagstrom and CM Montefusco

The technical feasibility and rejection characteristics of intrafamilial fox-to-dog xenografts were studied. The results indicate that (1) both lungs of a smaller donor can be successfully transplanted into a single hemithorax of a larger recipient, (2) fox-to-dog lung xenografts are capable of providing total pulmonary function at tolerable right ventricular pressures, and (3) the rejection process of unmodified intrafamilial lung xenografts, was similar to and not more vigorous or more rapid than that of canine lung allografts in untreated recipients.




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Copyright © 1981 by The American Association for Thoracic Surgery.