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The Journal of Thoracic and Cardiovascular Surgery, Vol 88, 217-224, Copyright © 1984 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
KS Iyer, KS Reddy, IM Rao, P Venugopal, ML Bhatia and N Gopinath
Prosthetic valve replacement in young patients has been reported to be
associated with a high mortality and morbidity because of valve-related
problems. Of 549 patients undergoing valve replacement with the Bjork-
Shiley valve prosthesis, 136 were under the age of 20 years. Sixty-four
patients were under 16 years of age, the youngest being 6 years old. Of the
136 patients, 61 underwent mitral valve replacement, 50 received an aortic
valve, and 25 received both aortic and mitral valves. Overall operative
mortality was 10.3%. Late mortality over a follow-up period of 6 months to
8 years was 4.4%. Actuarial survival curves up to 8 years of follow-up are
presented. Results obtained in this group are compared with those obtained
in 413 patients over 20 years of age operated during the same period. Valve
thrombosis was not seen in any patient under 20 years of age, but it
occurred in 4.13% of the patients over 20 years of age. The incidence of
thromboembolism and anticoagulant-related hemorrhage was very low. There
has been no instance of structural failure of the valve. Long-term results
are excellent, with 90% of the survivors returning to New York Heart
Association Functional Class I. The Bjork-Shiley valve gives excellent and
durable long-term palliation in young patients requiring valve replacement.
ARTICLES
Valve replacement in children under twenty years of age. Experience with the Bjork-Shiley prosthesis
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