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The Journal of Thoracic and Cardiovascular Surgery, Vol 88, 263-272, Copyright © 1984 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
RJ Peterson, RH Franch, WA Fajman, JG Jennings and RH Jones
The purpose of this investigation was to define mechanisms which increase
cardiac output during exercise in patients without a functioning right
ventricle. Radionuclide studies were performed at rest and during upright
bicycle exercise on 16 patients following Fontan procedures and compared to
studies in 10 normal children. The mean cardiac index of patients following
Fontan procedures was 5.2 +/- 2.0 L/min/m2 (standard deviation) at rest and
increased to 9.4 +/- 3.5 L/min/m2 during exercise (p less than 0.0001).
Exercise values were similar to those observed in normal children. The
mechanisms utilized to achieve high cardiac output following Fontan
procedures included an increase in heart rate. Mean systemic ventricular
ejection fractions were significantly less than in normal children. The
resting ventricular end-diastolic volume and stroke volume indices were
above normal and remained constant during exercise to high heart rates.
These data clearly document that a large exercise cardiac output can be
achieved by patients without a functioning right ventricle.
ARTICLES
Noninvasive determination of exercise cardiac function following Fontan operation
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M. Rosenthal, A. Bush, J. Deanfield, and A. Redington Comparison of Cardiopulmonary Adaptation During Exercise in Children After the Atriopulmonary and Total Cavopulmonary Connection Fontan Procedures Circulation, January 15, 1995; 91(2): 372 - 378. [Abstract] [Full Text] |
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