HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Danford, D. A. Articles by Gutgesell, H. P. Search for Related Content PubMed PubMed Citation Articles by Danford, D. A. Articles by Gutgesell, H. P.

The Journal of Thoracic and Cardiovascular Surgery, Vol 89, 610-615, Copyright © 1985 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Left ventricular wall stress and thickness in complete transposition of the great arteries. Implications for surgical intervention

DA Danford, JC Huhta and HP Gutgesell

The effects of volume and pressure loading of the left ventricle on posterior wall thickness and left ventricular wall stress in transposition of the great arteries were studied by combining echocardiographic and cardiac catheterization data. Pure volume loading with low left ventricular pressure resulted in little or no thickening of the left ventricular posterior wall (0.52 mm/log month). Pressure loading to levels above half of the right ventricular pressure was associated with thickening (2.80 to 3.89 mm/log month); however, further increase in pressure or volume load did not significantly alter the rate of thickening. Estimates of ventricular wall stress using a simple radius/wall thickness ratio may be misleading. However, if allowance is made for variable ventricular geometry and pressure, estimated wall stress is constant in transposition and is approximately equal to that reported previously in patients with normally related great arteries. The walls of low-pressure left ventricles in patients with transposition are demonstrably thinner than those of high-pressure left ventricles by age 1 to 3 months (2.67 versus 3.52 mm). Surgical procedures to use the left ventricle for systemic work, such as the arterial switch operation, should be performed in the first month of extrauterine life. Preparatory operations, if necessary prior to arterial switch, should load the left ventricle to greater than half systemic pressure.

This article has been cited by other articles:

				R. S. Assad, M. Cardarelli, M. C. Abduch, V. D. Aiello, M. Maizato, M. Barbero-Marcial, and A. Jatene Reversible pulmonary trunk banding with a balloon catheterAssessment of rapid pulmonary ventricular hypertrophy J. Thorac. Cardiovasc. Surg., July 1, 2000; 120(1): 66 - 72. [Abstract] [Full Text] [PDF]