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The Journal of Thoracic and Cardiovascular Surgery, Vol 89, 753-757, Copyright © 1985 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
MB Orringer, JC Sisson, G Glazer, B Shapiro, I Francis, DM Behrendt, NW Thompson and RV Lloyd
The development at our institution of the radiopharmaceutical 131-I-
metaiodobenzylguanidine has permitted for the first time scintigraphic
localization of pheochromocytomas. By the use of this scan in combination
with contrast-enhanced computed tomography, intrapericardial
pheochromocytomas have been demonstrated in eight patients at our hospital
during the past 2 years. Four of these patients have been operated upon by
us, and each was found to have a pheochromocytoma arising from the heart
(left atrium in three and interventricular groove at the aortic root in
one). While in one patient it was possible to "shell" the tumor away from
the left atrial wall without cardiopulmonary bypass, in the remaining
patients, bypass and cardioplegia were required to resect the
pheochromocytomas without inducing life-threatening intraoperative
hypertension and cardiac arrhythmias. One patient required coronary artery
reconstruction and two, excision of the posterior left atrial wall with
pericardial replacement. One of these latter two patients died
intraoperatively of uncontrollable hemorrhage. The three remaining patients
are well and normotensive after more than 1 year of follow-up. Cardiac
pheochromocytomas should not be approached as typical posterior mediastinal
tumors, or as they are in the abdomen, with the expectation that they will
"shell away" from contiguous structures. Cardiopulmonary bypass should be
available, and resection of involved myocardium may be necessary for
complete removal.
ARTICLES
Surgical treatment of cardiac pheochromocytomas
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