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The Journal of Thoracic and Cardiovascular Surgery, Vol 90, 901-906, Copyright © 1985 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
GW Christie, JB Gavin and BG Barratt-Boyes
The detachment of allograft tissue from supporting stent posts has been a
common mode of failure of stent-mounted aortic allografts. In an effort to
reduce the localized stress loading on the tissue at the top of the stent
posts, two changes were introduced to the previous fabrication protocol
followed by Green Lane Hospital. Specifically, they were the use of a
flexible acetyl-copolymer stent and covering of the peripheral attachment
sutures with a bias strip of Dacron cloth. This study showed that these
changes did not reduce the incidence of allograft failure caused by graft
detachment. Unexpectedly, covering antibiotic-treated allograft tissue with
a bias strip actually increased the likelihood of failure of the valve, by
accelerating the biological degradation of the underlying graft aortic
wall. The weakened aortic wall tissue was consequently less able to resist
the high stress loadings at the top of the stent posts where detachment
first occurred.
ARTICLES
Graft detachment, a cause of incompetence in stent-mounted aortic valve allografts
This article has been cited by other articles:
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B. G. Barratt-Boyes, W. M. Jaffe, and R. M. Whitlock THE MEDTRONIC INTACT* PORCINE VALVE: TEN-YEAR CLINICAL REVIEW J. Thorac. Cardiovasc. Surg., December 1, 1998; 116(6): 1005 - 1014. [Abstract] [Full Text] [PDF] |
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