The Journal of Thoracic and Cardiovascular Surgery, Vol 91, 248-251, Copyright © 1986 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Inhibition of pulmonary surfactant by plasma from normal adults and from patients having cardiopulmonary bypass
PT Phang and KM Keough
Plasma from normal adults and from children and adults having
cardiopulmonary bypass inhibited the ability of pulmonary surfactant to
reach low surface tension in proportion to the amount of protein added. No
increase in the extent of inhibition of surfactant action per milligram of
protein was seen in plasma taken before or after bypass in adults or
children.