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The Journal of Thoracic and Cardiovascular Surgery, Vol 91, 485-489, Copyright © 1986 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Heart and unilateral lung transplantation in the dog

A Kawaguchi, PD Hirsh, TC Wolfgang, AS Mills and RR Lower

A technique is presented for transplantation of the heart and left lung en bloc in the dog. In contrast to the erratic respiratory pattern that occurs in subprimate animals after total cardiopulmonary denervation, preservation of innervation to the native right lung results in a normal respiratory pattern in the dog and has allowed survival of one animal for 68 days. This model is proposed as potentially suitable for physiologic and immunologic studies of cardiopulmonary transplantation in the dog.


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M. Otaki, T. Inoue, T. Matsumoto, H. Kitayama, and H. Oku
Experimental Orthotopic Heart and Bilateral Lung Transplantation Completed Without Cardiopulmonary Bypass
Chest, November 1, 1999; 116(5): 1360 - 1364.
[Abstract] [Full Text] [PDF]


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Copyright © 1986 by The American Association for Thoracic Surgery.