JTCS Tips for Better Browsing
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mickleborough, L. L.
Right arrow Articles by Baird, R. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mickleborough, L. L.
Right arrow Articles by Baird, R. J.

The Journal of Thoracic and Cardiovascular Surgery, Vol 91, 779-787, Copyright © 1986 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Endocardial excision versus encircling endocardial ventriculotomy. A comparison of effects on ventricular structure and function

LL Mickleborough, GJ Wilson, RD Weisel, CA Mackay, J Ivanov, M Takagi, H Akagawa, PR McLaughlin and RJ Baird

Although endocardial excision and encircling endocardial ventriculotomy are being performed in patients with extensive triple-vessel disease and compromised ventricular function, long-term effects of the operative intervention on structure and function of the left ventricle have not been determined. These procedures were performed in healthy dogs in three groups: control (ventriculotomy alone), endocardial excision, and encircling endocardial ventriculotomy (five dogs per group). Six weeks later, through a left thoracotomy, an arterial line, left atrial line, and Swan-Ganz catheter were inserted. Cardiac output measurements permitted calculation of left ventricular stroke work index, and gated nuclear ventriculograms permitted calculation of left ventricular volume indices. Myocardial performance (stroke work index/end-diastolic volume index relation), systolic elastance (systolic blood pressure/end-systolic volume index relation) and diastolic pressure-volume relationship (left atrial pressure/end- diastolic volume index relation) were determined from volume loading studies. In the endocardial excision group, the left atrial pressures were increased at similar end-diastolic volumes (p less than 0.05 by performance and systolic elastance were similar in the three groups. On completion of hemodynamic studies, the hearts were excised. Gross and light microscopic examination showed that the inner layer of myocardium was scarred in the area of intervention after both endocardial excision and encircling endocardial ventriculotomy. In neither group was there significant morphologic change elsewhere in the myocardium. Both endocardial excision and encircling endocardial ventriculotomy have little effect on long-term structure and function when performed in healthy canine hearts.


This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
V. Rao, M. Komeda, R. D. Weisel, G. Cohen, M. A. Borger, and T. E. David
Should the pericardium be closed routinely after heart operations?
Ann. Thorac. Surg., February 1, 1999; 67(2): 484 - 488.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1986 by The American Association for Thoracic Surgery.