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The Journal of Thoracic and Cardiovascular Surgery, Vol 91, 874-878, Copyright © 1986 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Effects of preoperative glucose-insulin-potassium on myocardial glycogen levels and on complications of mitral valve replacement

GS Oldfield, PJ Commerford and LH Opie

Myocardial glycogen content was increased from a mean of 25.8 +/- 3.7 to 40.3 +/- 4.2 mumol/gm (p less than 0.0001) by an infusion of glucose, insulin, and potassium before mitral valve replacement. Patients who had received such an infusion and who had a higher myocardial glycogen content had a lower incidence of postoperative hypotension, less serious postoperative arrhythmias, and fewer serious complications after elective mitral valve replacement.

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