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The Journal of Thoracic and Cardiovascular Surgery, Vol 92, 691-705, Copyright © 1986 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
NT Kouchoukos, WG Marshall Jr and TA Wedige-Stecher
Between September, 1974, and December, 1985, 127 patients had replacement
of the ascending aorta and aortic valve with a composite graft.
Annuloaortic ectasia was the most common indication for operation (69
patients), followed by aortic dissection (51 patients). Twenty-four
patients (19%) had the Marfan syndrome. Hospital mortality was 4.7%.
Emergent operation for acute dissection was the only independent predictor
of hospital death (p = 0.03). Reoperation for postoperative hemorrhage was
required in 15 patients (11.8%) and for prosthesis-related complications
(pseudoaneurysm, prosthetic endocarditis, technical problems, and valve
thrombosis) in 16 patients (12.6%). Since we adopted a technique of
preclotting the prosthesis with whole blood or albumin plus autoclaving and
abandoned the inclusion technique, the reoperation rate has declined
substantially. At 5 years, the actuarial freedom from reoperation for any
reason on the ascending aorta or aortic valve for the 24 patients in whom
this modification was used was 90% and for the remaining 103 patients, 73%
(p = 0.17). No reoperations for pseudoaneurysms or technical problems were
required in these 24 patients, whereas 10 reoperations for these
complications were necessary in the other patients. The mean duration of
follow-up was 54 months. The actuarial survival rate at 7 years for the
entire group was 65%; for the patients with annuloaortic ectasia, 70%; for
those with aortic dissection, 61%; for the patients with the Marfan
syndrome, 57%. Actuarial freedom from operation on the remainder of the
aorta at 7 years was 89%, but it was 78% for the subgroup with the Marfan
syndrome. The satisfactory results with extended follow-up support the
continued use of the composite graft technique as the preferred method of
treatment for patients with annuloaortic ectasia or recurrent aneurysms of
the sinuses of Valsalva and for patients with aortic dissection who require
aortic valve replacement.
ARTICLES
Eleven-year experience with composite graft replacement of the ascending aorta and aortic valve
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