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The Journal of Thoracic and Cardiovascular Surgery, Vol 95, 705-711, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
O Matsuki, Y Okita, RS Almeida, JP McGoldrick, TL Hooper, A Robles and DN Ross
Aortic valve replacement with a pulmonary autograft was performed on 241
patients between June 1967 and October 1986 at National Heart Hospital,
Guy's Hospital, Middlesex Hospital, Harley Street Clinic, and Italian
Hospital in London by one of the authors (D.N.R.). The longest follow-up is
18 years 7 months, and the cumulative total follow-up is 1130 patient-years
(pt-yr). The overall 30-day mortality rate is 6.6% (16 patients), with no
deaths after 1976, and the late mortality rate is 1.7%/pt-yr (19 patients).
The actuarial survival rate is 57.3% +/- 9.6% at 19 years. No
anticoagulation has been used and there have been no thromboembolic
episodes. The incidence of bacterial endocarditis is 1.2%/pt-yr (14
patients), and its actuarial event-free rate is 74.2% +/- 8.1% at 19 years.
Reoperation because of failure of the pulmonary autograft was performed on
36 patients, 27 of whom needed valve replacement. The incidence of
pulmonary autograft replacement is 2.5%/pt-yr, and its actuarial event-free
rate is 48.5% +/- 13.7% at 19 years. For reconstruction of the right
ventricular outflow tract, 186 aortic homografts, 26 pulmonary homografts,
16 autologous fascia lata valved conduits, 7 autologous pericardial
conduits with or without a valve, and 6 xenograft valved Dacron conduits
were used. Thirty-one patients were reoperated on, mostly because of
degeneration of this material. Pulmonary rather than aortic homografts are
now favored for reconstruction of the right ventricular outflow tract
Because of its satisfactory long-term result without the need for
anticoagulation, as well as its safety as an established surgical
procedure, this operation can be recommended to a wider range of patients.
ARTICLES
Two decades' experience with aortic valve replacement with pulmonary autograft
National Heart Hospital, London, England.
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