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The Journal of Thoracic and Cardiovascular Surgery, Vol 96, 171-177, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
VW Rusch, JD Godwin and WP Shuman
Between October 1983 and April 1987, 20 patients with malignant
mesothelioma underwent computed tomography scans of the chest and upper
abdomen to evaluate the extent of disease before treatment. Twelve of these
20 patients deemed to have some potential for long-term survival had scans
performed every 3 months after operation to help detect recurrent disease.
Anatomic correlation of computed tomography scan findings was available in
all 20 patients. The limitations of computed tomography in initial
evaluation were its difficulties in assessing (1) chest wall involvement
(nine patients), (2) mediastinal lymph nodes (four patients), (3)
transdiaphragmatic extension of tumor (four patients), and (4) peritoneal
studding and solid organ metastases less than 2 mm in size (one patient).
Computed tomography was helpful in detecting recurrent disease in the 12
patients having long-term follow- up. In six of eight cases with
histologically proved recurrence, computed tomography detected tumors from
1 to 8 months before the onset of signs or symptoms. Although computed
tomography is known to provide far more information about the extent of
disease than plain radiographs, it remains an imperfect tool for the
staging of disease in patients with malignant mesothelioma. Despite its
limitations, computed tomography is probably the most accurate way to
provide follow-up for patients during treatment.
ARTICLES
The role of computed tomography scanning in the initial assessment and the follow-up of malignant pleural mesothelioma
Department of Surgery, University of Washington, Seattle 98195.
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