HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Starnes, V. A. Articles by Shumway, N. E. Search for Related Content PubMed PubMed Citation Articles by Starnes, V. A. Articles by Shumway, N. E.

The Journal of Thoracic and Cardiovascular Surgery, Vol 96, 62-71, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Isolated left ventricular assist as bridge to cardiac transplantation

VA Starnes, PE Oyer, PM Portner, N Ramasamy, PJ Miller, EB Stinson, JC Baldwin, AK Ream, J Wyner and NE Shumway
Department of Cardiovascular Surgery, Stanford University Medical Center 94305.

The electrically driven Novacor implantable left ventricular assist device has been implanted in six patients (four men and two women) since Sept. 7, 1984. In four of the six patients (67%) the device was a successful bridge to cardiac transplantation. One patient died of multiple organ failure and Candida sepsis after 16 days of support with the device. One patient died in the operating room of uncontrollable hemorrhage and biventricular failure caused by severe cardiac rejection. Three patients are alive with cardiac transplants 38, 17, and 10 months after transplantation. One patient died after cardiac transplantation of presumed sepsis. The Novacor left ventricular assist device performed in all cases without mechanical or electrical failure. Excluding the intraoperative death, assist duration ranged from 2 to 16 days. The cardiac index (synonymous with device output) ranged from 2.4 to 3.4 L/min/m2. No embolic events (cerebrovascular or systemic) occurred during assistance with the device. Minimal red cell hemolysis was documented during the period of support. The Novacor left ventricular assist device is a safe and effective bridge to cardiac transplantation in patients with refractory cardiogenic shock.

This article has been cited by other articles:

				L. W. Stephenson History of Cardiac Surgery Card. Surg. Adult, January 1, 2008; 3(2008): 3 - 28. [Full Text]

				M. J. Wilhelm, C. Schmid, and H. H. Scheld Reply to the Editor: J. Thorac. Cardiovasc. Surg., July 1, 2006; 132(1): 210 - 211. [Full Text] [PDF]

				M. J. Wilhelm, D. Hammel, C. Schmid, A. Rhode, T. Kaan, M. Rothenburger, J. Stypmann, M. Schafers, C. Schmidt, H. A. Baba, et al. Long-term support of 9 patients with the DeBakey VAD for more than 200 days J. Thorac. Cardiovasc. Surg., October 1, 2005; 130(4): 1122 - 1129. [Abstract] [Full Text] [PDF]

				M. E. DeBakey Development of Mechanical Heart Devices Ann. Thorac. Surg., June 1, 2005; 79(6): S2228 - S2231. [Abstract] [Full Text] [PDF]

				L. W. Stephenson History of Cardiac Surgery Card. Surg. Adult, January 1, 2003; 2(2003): 3 - 29. [Full Text]

				I. Di Bella, F. Pagani, C. Banfi, E. Ardemagni, A. Capo, C. Klersy, and M. Vigano Results with the Novacor assist system and evaluation of long-term assistance Eur. J. Cardiothorac. Surg., July 1, 2000; 18(1): 112 - 116. [Abstract] [Full Text] [PDF]

				R. C. Robbins, C. W. Barlow, P. E. Oyer, S. A. Hunt, J. L. Miller, B. A. Reitz, E. B. Stinson, and N. E. Shumway THIRTY YEARS OF CARDIAC TRANSPLANTATION AT STANFORD UNIVERSITY J. Thorac. Cardiovasc. Surg., May 1, 1999; 117(5): 939 - 951. [Abstract] [Full Text] [PDF]

				P. M. McCarthy, K. Fukamachi, F. Fukumura, K. Muramoto, L. A. R. Golding, and H. Harasaki The Cleveland Clinic-Nimbus total artificial heart: In vivo hemodynamic performance in calves and preclinical studies J. Thorac. Cardiovasc. Surg., September 1, 1994; 108(3): 420 - 428. [Abstract] [Full Text]

				D. G. Pennington, L. R. McBride, P. S. Peigh, L. W. Miller, and M. T. Swartz Eight years' experience with bridging to cardiac transplantation J. Thorac. Cardiovasc. Surg., February 1, 1994; 107(2): 472 - 481. [Abstract] [Full Text]

				J. Chalmers and T. Graham Review article : Mechanical ventricular support in the management of postcardiotomy cardiogenic shock Perfusion, October 1, 1989; 4(4): 243 - 253. [Abstract] [PDF]