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The Journal of Thoracic and Cardiovascular Surgery, Vol 96, 952-961, Copyright © 1988 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

In vitro comparison of aortic heart valve prostheses. Part 1: Mechanical valves

E Knott, H Reul, M Knoch, U Steinseifer and G Rau
Helmholtz-Institute for Biomedical Engineering, Aachen University of Technology, Federal Republic of Germany.

The hydrodynamic performance of a series of mechanical heart valve prostheses is measured in the aortic position. All experiments are performed in an electrohydraulic, computer-controlled pulse duplicator simulating the left side of the human circulatory system. Testing conditions are set according to a Food and Drug Administration interlaboratory comparison protocol with cardiac outputs of 3.0, 4.5, 6.5, and 8.0 L/min at a constant heart rate of 70 beats/min. Mean systolic pressure differences, volume losses, and energy losses, as well as dimensionless pressure losses and energy loss coefficients, are calculated from the recorded pressure, volume, and flow tracings. The results of 10 mechanical heart valve prostheses (eight tilting disc valves and two bileaflet valves) are presented and their clinical relevance is discussed.

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