The Journal of Thoracic and Cardiovascular Surgery, Vol 98, 942-944, Copyright © 1989 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
Successful human double-lung transplantation after five and one-half hours of preservation
RS Bonser, R Fischel, L Fragomeni, M Kaye, J Burdine, C Friese, J Kriett, S Shumway and SW Jamieson
Minnesota Heart and Lung Institute, University of Minnesota, Minneapolis 55455.
Successful clinical double-lung transplantation after 5 1/2 hours of
pulmonary ischemia is reported. Static hypothermic preservation with a
high-volume, high flow rate-modified Collin's solution pulmonary artery
flush was used. Excellent early and late pulmonary function demonstrates
the efficacy of the technique that is described in detail. Lung
transplantation remains limited by the lack of reliable methods of
long-term storage of donor organs, but refinement of current techniques may
soon allow its wider application.