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The Journal of Thoracic and Cardiovascular Surgery, Vol 98, 968-970, Copyright © 1989 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association


ARTICLES

Role of extracorporeal membrane oxygenation in selected pediatric respiratory problems

CW Lillehei, PP O'Rourke, JP Vacanti and RK Crone
Department of Surgery, Children's Hospital, Boston, MA 02115.

Between 1984 and 1988, 89 infants and children with severe respiratory failure were supported by extracorporeal membrane oxygenation. Major clinical diagnoses included congenital diaphragmatic hernias (34), meconium aspiration syndrome (26), and sepsis (8). Extracorporeal membrane oxygenation was used for patients with a predicted mortality rate of at least 80% based on an oxygenation index greater than 0.4. Venoarterial bypass was accomplished by way of right cervical cannulation of the common carotid artery and internal jugular vein. Overall survival was 71% but varied widely by diagnosis and progressively improved over time. The average extracorporeal membrane oxygenation run was 5.7 days. Intracranial hemorrhage was the most serious complication occurring in 16% of patients. Mechanical circuit complications were seen in 22% but rarely related to significant morbidity. Extracorporeal membrane oxygenation appears to provide effective cardiopulmonary support for selected pediatric respiratory problems. It affords those with potentially reversible pathophysiology the temporal opportunity for successful medical or surgical therapies.


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Arch. Dis. Child. Fetal Neonatal Ed.Home page
P J DAVIS and L S SHEKERDEMIAN
Meconium aspiration syndrome and extracorporeal membrane oxygenation
Arch. Dis. Child. Fetal Neonatal Ed., January 1, 2001; 84(1): 1F - 3.
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