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J Thorac Cardiovasc Surg 2003;125:417-418
© 2003 The American Association for Thoracic Surgery

Brief Communications

The last to die is hope: Prolonged mechanical circulatory support with a Novacor left ventricular assist device as a bridge to transplantation

Dino Casarotto, MD, Tomaso Bottio, MD, Antonio Gambino, MD, Luca Testolin, MD, Gino Gerosa, MD Padua, Italy

From the Department of Cardiovascular Surgery, University of Padua Medical School, Padua, Italy.

Received for publication Feb 26, 2002. Accepted for publication May 21, 2002. Address for reprints: Dino Casarotto, MD, Istituto di Chirurgia Cardiovascolare, Via Giustiniani, 1, 35121 Padova, Italy (E-mail: dino.casarotto@unipd.it).

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  		Bottio, Casarotto, Gerosa, Gambino, and Testolin (left to right).

 
In September 1996 a 31-year-old man was admitted to Padua Hospital, Padua, Italy, in cardiogenic shock that was not responsive to medical treatment and intra-aortic balloon pump insertion. The patient had Castleman disease, and in 1989 he was treated with cycles of cyclophosphamide, vincristine, mitoxantrone hydrochloride (INN: mitoxantrone), and interferon. In June 1996 at another hospital, he had postchemotherapy dilated cardiomyopathy diagnosed, with akinesia of septum and anterior left ventricle wall (end-diastolic volume 230 mL, end-systolic volume 180 mL, ejection fraction 20%, and left ventricular end-diastolic diameter 67 mm). Because of severe left ventricular failure, we started therapy with a BioMedicus left ventricular . . . [Full Text of this Article]




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