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J Thorac Cardiovasc Surg 2004;128:156
© 2004 The American Association for Thoracic Surgery

Letter to the editor

Reply to the Editor

Robert W. Grauss, MSc, Marco C. Deruiter, PhD, Mark G. Hazekamp, MD, PhD

Department of Anatomy and Embryology, and the Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands

The first 20% of the full text of this article appears below.

We thank Légaré and Ross for their comment on our article describing the in vivo behavior of decellularized rat aortic valve allografts. As they state in their letter, a complication of the model we used is the sinus thrombus formation observed in all decellularized synergrafts and allografts, as well as in the untreated allografts. They speculate that this is due mainly to a lack of leaflet mobility in a nonfunctional implantation model.1

To overcome this difficulty Légaré and . . . [Full Text of this Article]






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