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J Thorac Cardiovasc Surg 2005;129:1440-1442
© 2005 The American Association for Thoracic Surgery

Brief Communication

Giant metastatic myxoid liposarcoma of the mediastinum: A case report

Gabriele Di Giammarco, MD*, Michele Di Mauro, MD, Marco Pano, MD, Sergio Cirmeni, MD, Marco Contini, MD, Carlo Di Lorenzo, MD, Antonio Bivona, MD, Gerardo Liberti, MD

Division of Cardiac Surgery, University "G D’Annunzio," Chieti-Pescara, Chieti, Italy.

Received for publication December 10, 2004; accepted for publication January 10, 2005.

* Address for reprints: Gabriele Di Giammarco, MD, Chief of Division of Cardiac Surgery, University "G D’Annunzio," S Camillo Hospital, v Forlanini 50, 66100 Chieti, Italy (Email: gabriele.digiammarco1@tin.it).

The first 20% of the full text of this article appears below.

Myxoid liposarcoma is a very uncommon primary neoplasm in the mediastinum, representing 9% of all primary sarcomas in this area.1,2 It develops preferentially in the lower extremities (75%) and less frequently in the retroperitoneum.1 Myxoid liposarcoma usually metastasizes in the lungs and bone,1 and rarely in the mediastinum.3 The time interval between the first presentation and the pericardial metastasis ranges from 7 to 25 years.1 A case of giant metastatic myxoid liposarcoma in the pericardium causing cardiac tamponade is reported.

Clinical Summary

A 62-year-old man underwent 3 resections of a primary myxoid liposarcoma of the left thigh in 1983, 1985, and 1989. He was admitted to the hospital with reports of dyspnea for the previous 3 weeks and chest pain of recent onset. The computed tomography (CT) scan performed 6 months previously at a follow-up examination did not show any metastasis. No abnormalities were evident on the electrocardiogram. The chest radiography revealed a widened mediastinum. Echocardiography showed a big mass in the pericardium compressing the right sections . . . [Full Text of this Article]






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